It’s also possible that dizziness is related to an anxiogenic response that occurs among individuals taking extremely high doses or an interaction between ubiquinol and another substance you’re using. After switching back to regular CoQ10, ubiquinone, that went away completely. Another reason you might become dizzy from ubiquinol could be due to reducing your blood sugar more than expected, especially if you have diabetes and/or are using insulin. Insomnia: A ubiquinol side effect that’s seldom reported by users is insomnia. To help others get a better understanding of your situation, also provide specific details such as: your ubiquinol dose, the brand you were taking, whether you may have been allergic or sensitive to any ingredients, your usage of other substances (e.g. To manage the nausea, you may want to try taking ubiquinol after eating a large meal and avoid administering it along with other drugs or supplements. Headache 6. One might theorize that that irritability may be related to a significant increase in energy levels, whereby an individual becomes anxious and/or irritable from feeling overly energetic. Whether you experience any side effects from ubiquinol supplementation will be subject to significant individual variation. Though reducing LDL cholesterol below 40 mg/dL is highly unlikely to occur as a result of standalone ubiquinol, it’s possible that the supplemental ubiquinol may enhance reduction of LDL, leading to abnormalities. Included below is a list of side effects that have been reported by a subset of ubiquinol users. If you’re taking ubiquinol, you should always evaluate whether the health benefits of supplementation outweigh the side effects that you’re experiencing. Interestingly, some that have documented tiredness while taking ubiquinol report feeling better when taking CoQ10 (ubiquinone). It also notes some case reports of allergic reactions. Light sensitivity 11. This product usually has very few side effects. Although professionals consider ubiquinol supplementation to be extremely safe for most adults, rare adverse effects can occur, including: allergic reactions, appetite loss, diarrhea, headache, nausea, and stomach aches. On a scale of 1 to 10, with 1 being negligible and 10 being severe, what numeric rating would you assign to the side effects you experienced from ubiquinol? There are several influential variables that influence the specific ubiquinol side effects that you’ll experience, as well as their respective severities. Allergic reaction: An extremely small percentage of individuals might be allergic to ubiquinol and related products such as CoQ10 (ubiquinone) or idebenone. beta blocker) along with ubiquinol, it’s antihypertensive effect may be amplified with ubiquinol. It’s also possible that ubiquinol could induce sweating via an interaction with another substance (drug or supplement) or hormonal modulation. Started taking 100 mg of Ubiquinol 2 weeks ago. Ubiquinol supplementation led to a 1.5-fold increase in the amount of CoQ10 in the blood. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Loss of appetite 5. If you start taking ubiquinol and experience dizziness, there’s a chance that you may have initiated supplementation at too high of a dose. beta blocker) with their ubiquinol. Call your doctor for medical advice about side effects. Testing a different brand of ubiquinol (containing alternative ingredients to your current brand) may help determine whether an ingredient sensitivity was the cause of your headaches. Blood pressure changes: Some individuals might experience changes in blood pressure as a side effect of supplementing with ubiquinol. Notify me of followup comments via e-mail. Irritability: Only a few reports have been documented in which individuals experience irritability after supplementing with ubiquinol. Added ingredients: While most individuals are able to tolerate any brand of ubiquinol supplement without side effects, a subset of ubiquinol users will notice unwanted side effects and/or adverse reactions from one particular ubiquinol supplement and not another. That said, supplement companies may differ in terms of total ingredient composition within their ubiquinol product, as well as quality control. That said, you might also want to ensure that the ubiquinol isn’t somehow reducing your blood pressure (inducing a state of mild hypotension) whereby you could become sleepier than usual. A majority of individuals supplementing with ubiquinol on a daily basis won’t experience any noticeable or unwanted side effects. Reduced levels of Ubiquinol can also affect your LDL cholesterol. So far I have not noticed any side effects at all. Ubiquinol supplements are emulsified in an oil-based agent such as MCT oil which may irritate the GI tract, cause stomach aches, and ultimately diarrhea – especially in newer users. In the aforestated hypothetical scenario, it is likely that individual factors such as: a person’s age, co-administered substances, dietary intake of ubiquinol, genetics, and medical conditions – influenced the individually-distinct side effects experienced while taking ubiquinol. upset stomach, nausea, vomiting, loss of appetite; This is not a complete list of side effects and others may occur. hyperhidrosis) isn’t typically associated with ubiquinol, but may occur in reaction to added ingredients within the supplement and/or from administering an excessively large dose. Since ubiquinol is among the safest of all dietary supplements and most adults would benefit considerably from extra ubiquinol intake, it is likely to yield noticeable and/or measurable health benefits without triggering any unwanted side effects. Lexapro (Escitalopram) vs Zoloft (Sertraline): Extensive Comparison. Headache: Among the most common ubiquinol side effects reported by users is headaches. Side Effects. Anxiety: Although ubiquinol is understood to enhance energy levels, some individuals report experiencing such a significant energy spike, that it causes them to feel anxious. It is thought that individuals most likely to experience palpitations are those with underlying anxiety disorders and/or cardiovascular issues. Any reduction in appetite experienced while taking ubiquinol may be related to increases in energy levels from supplementation. However, biological aging interferes with a person’s ability to produce sufficient ubiquinol, and as a consequence, individuals over the age of 30 exhibit age-related increases in oxidative stress and cellular damage. low blood pressure. The anxiety may induce symptoms such as racing thoughts, insomnia, restlessness, agitation. Alter blood pressure. Prior to implementing any of the recommended strategies below, be sure to confirm the safety and hypothesized efficacy of each with a medical professional. Your best bet is to thoroughly evaluate the ingredients list of any ubiquinol supplement before purchasing to rule out possible allergies. Learn more about the benefits and side effects of this medication. Additionally, nausea might be triggered as a result of an allergic reaction to one of the ingredients within your particular supplement and/or ubiquinol interacting with another medication. The onset of flu-like symptoms after taking ubiquinol should be interpreted as an incompatibility between your body and the supplement you’re using, hence the reason you’re feeling sick. Despite favorably modulating insulin secretion, it appears as though some individuals taking ubiquinol may experience unexpected onset of low blood sugar or hypoglycemia. If the nausea fails to subside and/or intensifies, it’s probably a good idea to discontinue your ubiquinol and discuss the reaction with a medical doctor. Some individuals eat because they feel as if they are running low on energy, however, if their energy level significantly increases, it’s reasonable that appetite may decrease – perhaps more significantly than expected. The overstimulation effect may be associated with increased activity within the sympathetic branch of the autonomic nervous system, leading some individuals to experience palpitations or abnormal changes in heart rhythms. Understand that although ubiquinol is regarded as extremely safe, you should always listen to your body and discuss side effects you’re experiencing with a doctor. By Pina LoGiudice ND, LAc and Peter Bongiorno ND, LAc Directors of Inner Source Health There are many different brand of ubiquinol on the market, however, all of them contain Kaneka QH as the active ingredient. If you’ve taken ubiquinol and experienced side effects, feel free to report them in the comments section below. In the meantime, you may want to rule out potential interactions, contraindications, sensitivities, and allergies to the ingredients within your supplement. We comply with the HONcode standard for trustworthy health information -. One particular supplement company may engineer their ubiquinol product to contain certain ingredients to which you may be sensitive and/or allergic. Nausea, loss of appetite, upset stomach, or diarrhea may rarely occur. Some ubiquinol suppliers may sell a lower quality supplement containing cheap ingredients and/or oxidized oils that provoke side effects. For example, if you’re taking a stack of supplements to enhance mitochondrial function such as: PQQ, creatine, acetyl-l-carnitine, alpha-lipoid acid, and others – the synergistic energy increase may be overwhelming enough to keep you awake at night. In addition to the supplement company responsible for manufacturing your ubiquinol, you’ll also want to consider the seller. That said, insomnia may be nothing more than a transient side effect that diminishes with continued ubiquinol supplementation. In fact, ubiquinol and ubiquinone have very low toxicity. Note: A majority of ubiquinol supplements are devoid of dairy products (milk/egg-related), fish byproducts, nuts (e.g. Still, any fluctuations in concentrations and/or secretions of hormones resulting from ubiquinol might provoke unexpected reactions among certain users. This amplification could lead to greater reductions in your blood pressure than expected, possibly inducing a state of hypotension. If you’re feeling more keyed up and anxious while taking ubiquinol, the easiest solution is decreasing the dose to a level that makes you feel calm and/or able to function without excessive energy. Not all ubiquinol formulations are created equal nor do they contain the same inactive constituents, meaning its possible that you might be allergic and/or sensitive to an additive. Applies to ubiquinone: oral capsule, oral liquid, oral tablet, oral tablet disintegrating. Medical literature suggests that side effects and/or adverse reactions can occur in a subset of users, however, these occurrences are rare. Also realize that if you’re simultaneously using an antihypertensive agent (e.g. Another thing to consider is that the anxiety might indicate a sensitivity to one of the added ingredients. To counteract the occurrence of fatigue, you may want to try taking your ubiquinol at night (as opposed to first thing in the morning) so that fatigue won’t impair your performance. I have also felt slight light-headedness and some sinus headache symptoms. Monitor your blood sugar levels closely when introducing ubiquinol and report any significant changes to your doctor. It is possible that the majority of “side effects” reported by those supplementing may be unrelated to ubiquinol itself. That said, it may turn out that one user experiences low blood pressure whereas the other user reports diarrhea with increased energy. If the palpitations are becoming unbearable and/or seem to be getting worse, you may want to discontinue your ubiquinol or lower the dose. Stomach aches could also be related to an anxiogenic reaction to ubiquinol in which a user might notice an increase in his/her anxiety, and this anxiety may induce a stomach ache (rather than the ubiquinol). 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